HTLV1 Mutation Detail Information

> K88A Search Result

Mutation Information

Mutation Site	K88A
Mutation Type	Amino acid level
Gene/Protein/Region Type	Tax

Literature Information

PubMed PMID	22163338
Published Year	2011
Journal	Viruses
Title	Activation of LTRs from different human endogenous retrovirus (HERV) families by the HTLV-1 tax protein and T-cell activators.
Author	Toufaily C,Landry S,Leib-Mosch C,Rassart E,Barbeau B
Evidence	Both Tax K88A (Tax deficient for CBP/p300 recruitment) and Tax M47 (deficient for CREB activation) showed a limited induction of luciferase activity in transfected Jurkat cells when compared to wild-type Tax (Figure 3A).

Contents
Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation