|
Mutation Information
|
Mutation Site
|
K88A |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
Tax |
Literature Information
|
PubMed PMID
|
11046153
|
|
Published Year
|
2000 |
|
Journal
|
Molecular and cellular biology |
|
Title
|
Distinct p300-responsive mechanisms promote caspase-dependent apoptosis by human T-cell lymphotropic virus type 1 Tax protein. |
|
Author
|
Nicot C,Harrod R |
|
Evidence
|
The CBP/p300-binding defective Tax mutants K88A and V89A exhibited markedly reduced cytotoxic effects compared to the wild-type Tax protein.
|
|
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HTLV1 Mutation Detail Information