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Mutation Information
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Mutation Site
|
K88A |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
Tax |
Literature Information
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PubMed PMID
|
10766811
|
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Published Year
|
2000 |
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Journal
|
The Journal of biological chemistry |
|
Title
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p300 and p300/cAMP-responsive element-binding protein associated factor interact with human T-cell lymphotropic virus type-1 Tax in a multi-histone acetyltransferase/activator-enhancer complex. |
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Author
|
Harrod R,Kuo YL,Tang Y,Yao Y,Vassilev A,Nakatani Y,Giam CZ |
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Evidence
|
The Tax mutants (K88A and V89A) defective for p300/CBP-binding and LTR trans-activation, retained their abilities to interact with P/CAF.
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