Mutation Information
Mutation Site
|
K82R |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Genotype/Subtype
|
A |
Country
|
Russia |
Literature Information
PubMed PMID
|
25259833
|
Disease
|
HIV infection/AIDS
|
Published Year
|
2014 |
Journal
|
AIDS (London, England) |
Title
|
A uniquely prevalent nonnucleoside reverse transcriptase inhibitor resistance mutation in Russian subtype A HIV-1 viruses. |
Author
|
Kolomeets AN,Varghese V,Lemey P,Bobkova MR,Shafer RW |
Evidence
|
The nonpolymorphic RT mutation, K82R, occurred in 8.0% (24/300) of subtype A viruses, which is higher than its proportion in reverse transcriptase inhibitor (RTI)-naive (10/3072, 0.3%, P < 0.001) and RTI-experienced (2/1042, 0.2%, P < 0.001) patients with subtype A viruses in the Stanford HIVDB.
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