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Mutation Information
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Mutation Site
|
K70S |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Combined Mutation
|
rt.K101E+rt.K70S+rt.D67T+rt.K65R |
|
Country
|
Zambia |
Literature Information
|
PubMed PMID
|
32669382
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2020 |
|
Journal
|
Journal of clinical microbiology |
|
Title
|
A Comprehensive Genomics Solution for HIV Surveillance and Clinical Monitoring in Low-Income Settings. |
|
Author
|
Bonsall D,Golubchik T,de Cesare M,Limbada M,Kosloff B,MacIntyre-Cockett G,Hall M,Wymant C,Ansari MA,Abeler-Dörner L,Schaap A,Brown A,Barnes E,Piwowar-Manning E,Eshleman S,Wilson E,Emel L,Hayes R,Fidler S,Ayles H,Bowden R,Fraser C,HPTN 071 (PopART) Team. |
|
Evidence
|
In the same transmission pair, subpopulations of wild-type susceptible virus and dual-class NRTI/NNRTI resistant virus (K65R/D67T/K70S/K101E and K70N/K101E) were not transmitted to the recipient, probably because they were detected in the transmitter at low frequency (<5%).
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HIV Mutation Detail Information