HIV Mutation Detail Information

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Mutation Information

Mutation Site	K70R
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT

Literature Information

PubMed PMID	18547911
Published Year	2008
Journal	The Journal of biological chemistry
Title	Connection domain mutations N348I and A360V in HIV-1 reverse transcriptase enhance resistance to 3'-azido-3'-deoxythymidine through both RNase H-dependent and -independent mechanisms.
Author	Ehteshami M,Beilhartz GL,Scarth BJ,Tchesnokov EP,McCormick S,Wynhoven B,Harrigan PR,Götte M
Evidence	Furthermore, A360V was highly correlated with various mutations considered to be part of the TAMs cluster;for example, of the samples with A360V, 35% were associated with M41L, 21% with D67N, 30% with K70R, 17% with L210W, 42% with T215Y/F, and 17% with K219Q/E.

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation