Mutation Information
Mutation Site
|
K70R |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
PR |
Viral Reference
|
K03455.1
|
Literature Information
PubMed PMID
|
16524459
|
Disease
|
HIV infection/AIDS
|
Published Year
|
2006 |
Journal
|
BMC infectious diseases |
Title
|
DR_SEQAN: a PC/Windows-based software to evaluate drug resistance using human immunodeficiency virus type 1 genotypes. |
Author
|
Garriga C,Menéndez-Arias L |
Evidence
|
However, mutational patterns conferring resistance to zalcitabine, didanosine, stavudine and abacavir are complex, and the contribution of thymidine analogue resistance mutations (M41L, D67N, K70R, L210W, T215F/Y, K219Q/E) is poorly-defined in vivo, particularly when other mutations such as L74V or M184V are present.
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