HIV Mutation Detail Information

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Mutation Information

Mutation Site	K70N
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Combined Mutation	rt.K101E+rt.K70N
Country	Zambia

Literature Information

PubMed PMID	32669382
Disease	HIV infection/AIDS
Published Year	2020
Journal	Journal of clinical microbiology
Title	A Comprehensive Genomics Solution for HIV Surveillance and Clinical Monitoring in Low-Income Settings.
Author	Bonsall D,Golubchik T,de Cesare M,Limbada M,Kosloff B,MacIntyre-Cockett G,Hall M,Wymant C,Ansari MA,Abeler-Dörner L,Schaap A,Brown A,Barnes E,Piwowar-Manning E,Eshleman S,Wilson E,Emel L,Hayes R,Fidler S,Ayles H,Bowden R,Fraser C,HPTN 071 (PopART) Team.
Evidence	In the same transmission pair, subpopulations of wild-type susceptible virus and dual-class NRTI/NNRTI resistant virus (K65R/D67T/K70S/K101E and K70N/K101E) were not transmitted to the recipient, probably because they were detected in the transmitter at low frequency (<5%).

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation