|
Mutation Information
|
Mutation Site
|
K70N |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
NRTIs |
|
Country
|
America |
Literature Information
|
PubMed PMID
|
29846534
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2019 |
|
Journal
|
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America |
|
Title
|
Trends in the Molecular Epidemiology and Genetic Mechanisms of Transmitted Human Immunodeficiency Virus Type 1 Drug Resistance in a Large US Clinic Population. |
|
Author
|
Rhee SY,Clutter D,Fessel WJ,Klein D,Slome S,Pinsky BA,Marcus JL,Hurley L,Silverberg MJ,Kosakovsky Pond SL,Shafer RW |
|
Evidence
|
The thymidine analogue mutations, M184V/I and the tenofovir-associated DRMs K65R and K70E/Q/G/N/T accounted for 82.9%, 7.3%, and 1.4% of NRTI-associated TDR, respectively.
|
|
|
HIV Mutation Detail Information