HIV Mutation Detail Information

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Mutation Information

Mutation Site	K70E
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Viral Reference	HXB2
Relevant Drug	NRTIs
Country	China

Literature Information

PubMed PMID	33668946
Disease	HIV infection/AIDS
Published Year	2021
Journal	Pathogens (Basel, Switzerland)
Title	HIV Drug Resistance Mutations Detection by Next-Generation Sequencing during Antiretroviral Therapy Interruption in China.
Author	Li M,Liang S,Zhou C,Chen M,Liang S,Liu C,Zuo Z,Liu L,Feng Y,Song C,Xing H,Ruan Y,Shao Y,Liao L
Evidence	However, some minority DRMs at frequencies of 1%-5% disappeared, including N83D with PI-related, K70E, T215A, and K219E with NRTI-related and K101E, Y181C, H221Y and K238T with NNRTI-related, while others emerged, such as NNRTI-related V106A in patient GX088 at a frequency of 8.7%, and L23I, I47V and I84V with PI-related, D67N and F77L with NRTI-related and L100V and F227L with NNRTI-related, which appeared at frequencies of 1%-5% (Figure 3).

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation