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Mutation Information
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Mutation Site
|
K70E |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
bictegravir (BIC);emtricitabine (FTC);tenofovir alafenamide (TAF);dolutegravir (DTG) |
Literature Information
|
PubMed PMID
|
32701823
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2020 |
|
Journal
|
Journal of acquired immune deficiency syndromes (1999) |
|
Title
|
Switching to Bictegravir/Emtricitabine/Tenofovir Alafenamide (B/F/TAF) From Dolutegravir (DTG)+F/TAF or DTG+F/Tenofovir Disoproxil Fumarate (TDF) in the Presence of Pre-existing NRTI Resistance. |
|
Author
|
Acosta RK,Willkom M,Andreatta K,Liu H,Martin R,Parvangada A,Martin H,Collins S,White KL |
|
Evidence
|
And zidovudine (AZT).2431 TAMs (M41L, D67N, K70R,.
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|
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HIV Mutation Detail Information