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HIV Mutation Detail Information

> K70A Search Result


Mutation Information
Mutation Site K70A
Mutation Type Amino acid level
Gene/Protein/Region Type CA
Literature Information
PubMed PMID 17967060
Published Year 2007
Journal PLoS pathogens
Title Evidence for direct involvement of the capsid protein in HIV infection of nondividing cells.
Author Yamashita M,Perez O,Hope TJ,Emerman M
Evidence Importantly, the reduction of virus infectivity by itself does not necessarily cause the defect in the cell-cycle independence for infection, because some CA mutants that exhibit reduced overall infectivity still maintain the same property to infect nondividing cells as efficiently as dividing cells (for example, the P38A and K70A mutations;Figure 1A).
Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation