HPV Mutation Detail Information

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Mutation Information

Mutation Site	K68T
Mutation Type	Amino acid level
Gene/Protein/Region Type	E6
Genotype/Subtype	HPV16
Viral Reference	NC_001526.2
Country	Mexico

Literature Information

PubMed PMID	25889023
Disease	Low grade squamous intraepithelial lesion; High grade squamous intraepithelial lesion; Cervical carcinoma; Squamous-cell carcinoma
Published Year	2015
Journal	Virology journal
Title	Association of human papillomavirus 16 E6 variants with cervical carcinoma and precursor lesions in women from Southern Mexico.
Author	Ortiz-Ortiz J,Alarcón-Romero Ldel C,Jiménez-López MA,Garzón-Barrientos VH,Calleja-Macías I,Barrera-Saldaña HA,Leyva-Vázquez MA,Illades-Aguiar B
Evidence	Eight new E6 variants were found and 2 of them lead to amino acid change: E-C183/G350 (I27T) and E-C306/G350 (K68T).

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation