HIV Mutation Detail Information

> K65R Search Result

Mutation Information

Mutation Site	K65R
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Relevant Drug	tenofovir (TDF);emtricitabine (FTC)
Country	French

Literature Information

PubMed PMID	33724373
Disease	HIV infection/AIDS
Published Year	2021
Journal	The Journal of antimicrobial chemotherapy
Title	Tenofovir disoproxil fumarate and emtricitabine maintenance strategy in virologically controlled adults with low HIV-1 DNA: 48 week results from a randomized, open-label, non-inferiority trial.
Author	Prazuck T,Verdon R,Le Moal G,Ajana F,Bernard L,Sunder S,Roncato-Saberan M,Ponscarme D,Etienne M,Viard JP,Pasdeloup T,Darasteanu I,Pialoux G,de la Blanchardière A,Avettand-Fènoël V,Parienti JJ,Hocqueloux L,TRULIGHT Study Team .
Evidence	Six VFs occurred in the tenofovir disoproxil fumarate/emtricitabine arm (two with emerging mutations M184V and K65R) versus two in the control arm (ITT difference 3.5%, 95% CI -1.9 to 9.4).

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation