HIV Mutation Detail Information

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Mutation Information

Mutation Site	K65R
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Genotype/Subtype	C
Relevant Drug	NRTIs
Country	South Africa

Literature Information

PubMed PMID	33632139
Disease	HIV infection/AIDS
Published Year	2021
Journal	BMC infectious diseases
Title	Increased acquired protease inhibitor drug resistance mutations in minor HIV-1 quasispecies from infected patients suspected of failing on national second-line therapy in South Africa.
Author	Obasa AE,Ambikan AT,Gupta S,Neogi U,Jacobs GB
Evidence	The majority of the drug resistance mutations in the minor viral quasispecies were observed in the V82A mutation (n = 13) in protease and K65R (n = 5), K103N (n = 7) and M184V (n = 5) in reverse transcriptase.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation