|
Mutation Information
|
Mutation Site
|
K65R |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
tenofovir (TDF) |
|
Country
|
sub‐Saharan Africa;South Asia;Southeast Asia;Latin America;Caribbean |
Literature Information
|
PubMed PMID
|
32936523
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2020 |
|
Journal
|
Journal of the International AIDS Society |
|
Title
|
HIV-1 transmitted drug resistance surveillance: shifting trends in study design and prevalence estimates. |
|
Author
|
Rhee SY,Kassaye SG,Barrow G,Sundaramurthi JC,Jordan MR,Shafer RW |
|
Evidence
|
Among the NRTI resistance mutations, K65R had a significant increase in prevalence from 0.03% to 0.35% in sub‐Saharan Africa, whereas M184V had a non‐significant increase from 0.65% to 1.05%.
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HIV Mutation Detail Information