|
Mutation Information
|
Mutation Site
|
K65R |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
NRTIs |
|
Country
|
Kenya;Malawi;South Africa;South Africa;Kenya;Malawi |
Literature Information
|
PubMed PMID
|
32761071
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2020 |
|
Journal
|
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America |
|
Title
|
HIV drug resistance, phylogenetic analysis, and superinfection among men who have sex with men and transgender women in sub-Saharan Africa: HPTN 075. |
|
Author
|
Sivay MV,Palumbo PJ,Zhang Y,Cummings V,Guo X,Hamilton EL,McKinstry L,Ogendo A,Kayange N,Panchia R,Dominguez K,Chen YQ,Sandfort TGM,Eshleman SH |
|
Evidence
|
The presence of circulating HIV strains with the K65R and M184V mutations could compromise the use of current PrEP regimens in this population.
|
|
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HIV Mutation Detail Information