Mutation Information
Mutation Site
|
K65R |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Relevant Drug
|
NRTIs |
Country
|
Zimbabwe |
Literature Information
PubMed PMID
|
32522826
|
Disease
|
HIV infection/AIDS
|
Published Year
|
2020 |
Journal
|
Journal of clinical microbiology |
Title
|
Diagnostic Accuracy of Pan-Degenerate Amplification and Adaptation Assay for HIV-1 Drug Resistance Mutation Analysis in Low- and Middle-Income Countries. |
Author
|
Kouamou V,Manasa J,Katzenstein D,McGregor AM,Ndhlovu CE,Makadzange T |
Evidence
|
In a cross-sectional study (June 2018 to September 2019), we evaluated the diagnostic accuracy of a simple and rapid HIVDR assay (the pan-degenerate amplification and adaptation [PANDAA] assay targeting the mutations K65R, K103NS, M184VI, Y181C, and G190A) compared to Sanger sequencing and next-generation sequencing (NGS).
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