|
Mutation Information
|
Mutation Site
|
K65R |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
tenofovir (TDF) |
|
Country
|
Philippines |
Literature Information
|
PubMed PMID
|
32081778
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2020 |
|
Journal
|
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases |
|
Title
|
High rates of tenofovir failure in a CRF01_AE-predominant HIV epidemic in the Philippines. |
|
Author
|
Salvana EMT,Samonte GMJ,Telan E,Leyritana K,Tactacan-Abrenica RJ,Ching PR,Arevalo GM,Dungca NT,Peñalosa-Ramos C,Mendoza KAR,Trinidad LF,Tonga AD,Lim J,Destura R,Alejandria M,Solante R,Arcangel L,Palaypayon NS,Schwem BE |
|
Evidence
|
Higher rates of NRTI, NNRTI, K65R tenofovir resistance, and multi-class resistance were found compared to those reported in literature.
|
|
|
HIV Mutation Detail Information