HIV Mutation Detail Information

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Mutation Information

Mutation Site	K65R
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Relevant Drug	NNRTIs
Country	Asia;Sub-saharan Africa;Europe;North America

Literature Information

PubMed PMID	31774913
Disease	HIV infection/AIDS
Published Year	2020
Journal	The Journal of infectious diseases
Title	Human Immunodeficiency Virus-1 Viral Load Is Elevated in Individuals With Reverse-Transcriptase Mutation M184V/I During Virological Failure of First-Line Antiretroviral Therapy and Is Associated With Compensatory Mutation L74I.
Author	Gregson J,Rhee SY,Datir R,Pillay D,Perno CF,Derache A,Shafer RS,Gupta RK
Evidence	We repeated this process in subgroups of patients defined by several baseline characteristics: presence of K65R mutation, presence of major NNRTI mutations, choice of NRTI, choice of NNRTI, categories of baseline CD4 count (< and >200 cells/mm3), and categories of baseline VL (< and >100 000 copies per mL).

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation