|
Mutation Information
|
Mutation Site
|
K65R |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
NNRTIs |
Literature Information
|
PubMed PMID
|
31269034
|
|
Published Year
|
2019 |
|
Journal
|
PloS one |
|
Title
|
Drug resistance from preferred antiretroviral regimens for HIV infection in South Africa: A modeling study. |
|
Author
|
Abbas UL,Glaubius RL,Ding Y,Hood G |
|
Evidence
|
We constructed a stochastic individual-based model and simulated scenarios of ART implementation, either CD4-based (threshold < 500 cells/mL) or Fast-track (81% coverage by 2020), with consideration of major drug-associated mutations (M184V, K65R and non-nucleoside reverse transcriptase inhibitor (NNRTI)).
|
|
|
HIV Mutation Detail Information