Mutation Information
Mutation Site
|
K65R |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Relevant Drug
|
NRTIs;RT1t49 |
Literature Information
PubMed PMID
|
16207371
|
Published Year
|
2005 |
Journal
|
AIDS research and therapy |
Title
|
HIV-1 reverse transcriptase mutations that confer decreased in vitro susceptibility to anti-RT DNA aptamer RT1t49 confer cross resistance to other anti-RT aptamers but not to standard RT inhibitors. |
Author
|
Fisher TS,Joshi P,Prasad VR |
Evidence
|
This result was tempered by the observation that NRTI-resistance mutations such as K65R can confer resistance to some anti-RT aptamers.
|
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