HIV Mutation Detail Information

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Mutation Information
Mutation Site K657R
Mutation Type Amino acid level
Gene/Protein/Region Type Pol
Immune Escape Y
Country Vietnam
Literature Information
PubMed PMID 33031103
Disease HIV infection/AIDS
Published Year 2021
Journal AIDS (London, England)
Title Critical effect of Pol escape mutations associated with detrimental allele HLA-C*15: 05 on clinical outcome in HIV-1 subtype A/E infection.
Author Murakoshi H,Chikata T,Akahoshi T,Zou C,Borghan MA,Van Tran G,Nguyen TV,Van Nguyen K,Kuse N,Takiguchi M
Evidence On the other hand, no significant difference in CD4+ cell count (Fig. ​(Fig.2a)2a) or in pVL (Fig. S2) was found between HLA-C∗15:05+ individuals infected with the wild-type virus and those with the Pol I655V or Pol K657R virus.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation