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Mutation Information
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Mutation Site
|
K586R |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
EBNA1 |
|
Viral Reference
|
NC_009334.1;
NC007605.1 |
|
Country
|
Kenyan |
Literature Information
|
PubMed PMID
|
25933165
|
|
Published Year
|
2015 |
|
Journal
|
PloS one |
|
Title
|
Epstein-Barr virus genetic variation in lymphoblastoid cell lines derived from Kenyan pediatric population. |
|
Author
|
Simbiri KO,Smith NA,Otieno R,Wohlford EE,Daud II,Odada SP,Middleton F,Rochford R |
|
Evidence
|
Amino acid changes in the EBNA1 were in position 543 (M>T), 586 (K>R), and 599(S>N) in the C-terminal locus that has been associated with CD4+/CD8+ T cell binding. Significantly, LCL10 had no non-synonymous SNPs in BLLF1, and few in BPLF1 and BRRF2.
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EBV Mutation Detail Information