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Mutation Information
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Mutation Site
|
K50A |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
Vif |
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Combined Mutation
|
vif.K50A+vif.P49A |
Literature Information
|
PubMed PMID
|
28302150
|
|
Published Year
|
2017 |
|
Journal
|
Retrovirology |
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Title
|
Identification of a tripartite interaction between the N-terminus of HIV-1 Vif and CBFβ that is critical for Vif function. |
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Author
|
Desimmie BA,Smith JL,Matsuo H,Hu WS,Pathak VK |
|
Evidence
|
In addition, we included double mutants P49A-K50A and I51-S52A, because of their proximity to other double mutants that showed significant defects in CBFbeta binding.
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HIV Mutation Detail Information