|
Mutation Information
|
Mutation Site
|
K454T |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
L1 |
|
Genotype/Subtype
|
HPV16 |
|
Viral Reference
|
NC_001526.4
|
|
Country
|
India |
Literature Information
|
PubMed PMID
|
31944308
|
|
Disease
|
Cervical intraepithelial neoplasia
|
|
Published Year
|
2020 |
|
Journal
|
Journal of medical virology |
|
Title
|
Characterization of major capsid protein (L1) variants of Human papillomavirus type 16 by cervical neoplastic status in Indian women: Phylogenetic and functional analysis. |
|
Author
|
Mane A,Patil L,Limaye S,Nirmalkar A,Kulkarni-Kale U |
|
Evidence
|
Sixty-one SNPs were detected in L1 genes resulting in 20 non-synonymous amino acid substitutions of which N56T, N92T, L158F, V178G, N181I, K236T, K443Q, K454T and K475R are reported in Indian isolates for the first time.
|
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HPV Mutation Detail Information