|
Mutation Information
|
Mutation Site
|
K442N |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
L1 |
|
Amino acid_Mutation
|
A6964C |
|
Genotype/Subtype
|
HPV16 |
|
Viral Reference
|
U89348
|
|
Country
|
India |
Literature Information
|
PubMed PMID
|
18199779
|
|
Disease
|
Cervical carcinoma
|
|
Published Year
|
2008 |
|
Journal
|
Journal of clinical microbiology |
|
Title
|
Human papillomavirus type 16 variant analysis of E6, E7, and L1 genes and long control region in biopsy samples from cervical cancer patients in north India. |
|
Author
|
Pande S,Jain N,Prusty BK,Bhambhani S,Gupta S,Sharma R,Batra S,Das BC |
|
Evidence
|
Of four variants found independently (Fig. (Fig.2),2), two were silent mutations, A6667C and A6691G, coding for serine at codons 343 and 351, whereas A6803T and A6964C led to the missense mutations threonine→serine (T389S) and lysine→asparagine (K442N).
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HPV Mutation Detail Information