HIV Mutation Detail Information

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Mutation Information
Mutation Site K43E
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Genotype/Subtype B
Relevant Drug NRTIs
Literature Information
PubMed PMID 17500586
Disease HIV infection/AIDS
Published Year 2007
Journal PLoS computational biology
Title HIV-1 subtype B protease and reverse transcriptase amino acid covariation.
Author Rhee SY,Liu TF,Holmes SP,Shafer RW
Evidence Positively associated mutation pairs consisted primarily of Type I or II thymidine analog mutations (TAMs;as defined in Methods);accessory NRTI mutations that occurred in combination with Type I or II TAMs (K43E, E44D, V118I, H208Y, D218E);and Q151M-associated mutations (V75I, F77L, F116Y).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation