Mutation Information
Mutation Site
|
K36R |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
Vif |
Combined Mutation
|
vif.K36R+vif.R33G+vif.I31V |
Literature Information
PubMed PMID
|
32446377
|
Published Year
|
2020 |
Journal
|
Biochemical and biophysical research communications |
Title
|
Critical role of PP2A-B56 family protein degradation in HIV-1 Vif mediated G2 cell cycle arrest. |
Author
|
Nagata K,Shindo K,Matsui Y,Shirakawa K,Takaori-Kondo A |
Evidence
|
We expressed six NL4-3 Vif mutants, I31V/R33G/K36R, I31V, R33G, K36R, T47P/K50R, and H48 N, individually, in 293T cells and analyzed their effects on cell cycle.
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