|
Mutation Information
|
Mutation Site
|
K360E |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
IN |
Literature Information
|
PubMed PMID
|
25383358
|
|
Published Year
|
2014 |
|
Journal
|
Molecular therapy. Methods & clinical development |
|
Title
|
Efficient Transduction of LEDGF/p75 Mutant Cells by Gain-of-Function HIV-1 Integrase Mutant Viruses. |
|
Author
|
Wang H,Shun MC,Li X,Di Nunzio F,Hare S,Cherepanov P,Engelman A |
|
Evidence
|
WT and RR single-round constructs, and knockout MEFs expressing WT, EEE, or E4 (EEE with an added K360E change) LEDGF/p75 were infected with WT, RR, K42E, and RRE HIV-Luc.
|
|
|
HIV Mutation Detail Information