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Mutation Information
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Mutation Site
|
K315A |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
Gp120 |
|
Viral Reference
|
K03455.1
|
Literature Information
|
PubMed PMID
|
24897520
|
|
Published Year
|
2014 |
|
Journal
|
PloS one |
|
Title
|
The variable loop 3 in the envelope glycoprotein is critical for the atypical coreceptor usage of an HIV-1 strain. |
|
Author
|
Xiang Y,Liu W,Chen Y,Zhang C,Su W,Zhang Y,Sun J,Gao F,Jiang C |
|
Evidence
|
Six alanine mutants (V307A, E314A, K315A, V316A, Y317A and F318A) completely lost their ability to infect GPR15+ cells.
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HIV Mutation Detail Information