|
Mutation Information
|
Mutation Site
|
K297R |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
BXLF1 |
Literature Information
|
PubMed PMID
|
15779905
|
|
Published Year
|
2005 |
|
Journal
|
Biochemistry |
|
Title
|
Characterization of three essential residues in the conserved ATP-binding region of Epstein-Barr virus thymidine kinase. |
|
Author
|
Wu CC,Hsu TY,Chen JY |
|
Evidence
|
These results suggested that G294 participates in ATP binding and contributes to maintenance of structure. EBV TK mutants K297E, K297Q, and K297R lost their ATP-binding ability and enzyme activity.
|
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EBV Mutation Detail Information