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Mutation Information
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Mutation Site
|
K27T |
|
Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
S |
Literature Information
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PubMed PMID
|
28045894
|
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Published Year
|
2017 |
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Journal
|
PloS one |
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Title
|
Investigation of a Novel Hepatitis B Virus Surface Antigen (HBsAg) Escape Mutant Affecting Immunogenicity. |
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Author
|
Hossain MG,Ueda K |
|
Evidence
|
The multiple amino acid substitutions were located both within the MHR of W3S and outside of it, resulting in the mutants W3S VDCR98-101LDYQ (V98L/C100Y/R101Q), K27T (K27T/VDCR98-101LDYQ), G204S (K27T/VDCR98-101LDYQ/G204S), and F213L (K27T/VDCR98-101LDYQ/G204S/F213L) (Fig 1B).
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HBV Mutation Detail Information