Mutation Information
Mutation Site
|
K27F |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
Vpr |
Literature Information
PubMed PMID
|
18039376
|
Published Year
|
2007 |
Journal
|
Retrovirology |
Title
|
Localization of HIV-1 Vpr to the nuclear envelope: impact on Vpr functions and virus replication in macrophages. |
Author
|
Jacquot G,Le Rouzic E,David A,Mazzolini J,Bouchet J,Bouaziz S,Niedergang F,Pancino G,Benichou S |
Evidence
|
The potential structural modifications induced by substitution of Leu23 and Lys27 in Phe and Met, respectively, have been calculated by homology with the wild type Vpr protein using the Swiss-Model program.
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