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HIV Mutation Detail Information

> K25N Search Result


Mutation Information
Mutation Site K25N
Mutation Type Amino acid level
Gene/Protein/Region Type CA
Literature Information
PubMed PMID 33524070
Published Year 2021
Journal PLoS pathogens
Title A lysine ring in HIV capsid pores coordinates IP6 to drive mature capsid assembly.
Author Renner N,Mallery DL,Faysal KMR,Peng W,Jacques DA,Böcking T,James LC
Evidence However, the K25A and K25N mutants showed a profound loss of infectivity, with a reduction relative to wild-type of > 3 logs (Fig 2A and 2B).
Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation