|
Mutation Information
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Mutation Site
|
K22A |
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Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
Vif |
|
Viral Reference
|
K03455.1
|
Literature Information
|
PubMed PMID
|
31665623
|
|
Published Year
|
2019 |
|
Journal
|
Cell reports |
|
Title
|
HIV-1 Vif Triggers Cell Cycle Arrest by Degrading Cellular PPP2R5 Phospho-regulators. |
|
Author
|
Salamango DJ,Ikeda T,Moghadasi SA,Wang J,McCann JL,Serebrenik AA,Ebrahimi D,Jarvis MC,Brown WL,Harris RS |
|
Evidence
|
Moreover, all of these single amino acid substitution mutants could efficiently decrease APOBEC3G-EGFP levels, except for K22A and K26A, which are known to be required for APOBEC3G degradation.
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HIV Mutation Detail Information