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Mutation Information
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Mutation Site
|
K219S |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
IN |
Literature Information
|
PubMed PMID
|
19014951
|
|
Published Year
|
2009 |
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Journal
|
Journal of molecular biology |
|
Title
|
Defining the DNA substrate binding sites on HIV-1 integrase. |
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Author
|
Dolan J,Chen A,Weber IT,Harrison RW,Leis J |
|
Evidence
|
This hypothesis is supported by the in vitro activity phenotype of HIV-1 IN mutant with a K219S substitution showing loss in strand transfer activity while maintaining 3' processing on a HIV-1 substrate.
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HIV Mutation Detail Information