Mutation Information
Mutation Site
|
K219R |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Genotype/Subtype
|
RF02_AG |
Viral Reference
|
K03455.1
|
Relevant Drug
|
NRTIs |
Country
|
Cameroon |
Literature Information
PubMed PMID
|
32692778
|
Disease
|
HIV infection/AIDS
|
Published Year
|
2020 |
Journal
|
PloS one |
Title
|
Pre-treatment drug resistance and HIV-1 genetic diversity in the rural and urban settings of Northwest-Cameroon. |
Author
|
Fokam J,Takou D,Teto G,Nforbih SE,Kome OP,Santoro MM,Ngoufack ES,Eyongetah M,Palmer D,Fokunang ET,Fokunang CN,Colizzi V,Perno CF,Ndjolo A |
Evidence
|
Fifteen (15) PDR mutations were found among four patients the urban settings [6 resistance mutations to NRTIs:[M41L (2), E44D (1), K65R (1), K70E (1), M184V/I (2), K219R (1)] and 6 resistance mutations to NNRTIs: K103N (1), E138A/G (2), V179E (1), M230L (1), K238T (1), P225H (1)] against two (02) mutations found in two patients in the rural setting[2 resistant mutations to NNRTIs: E138A (1) and Y188H (1)].
|
|
|