HIV Mutation Detail Information

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Mutation Information

Mutation Site	K219Q
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT

Literature Information

PubMed PMID	18547911
Published Year	2008
Journal	The Journal of biological chemistry
Title	Connection domain mutations N348I and A360V in HIV-1 reverse transcriptase enhance resistance to 3'-azido-3'-deoxythymidine through both RNase H-dependent and -independent mechanisms.
Author	Ehteshami M,Beilhartz GL,Scarth BJ,Tchesnokov EP,McCormick S,Wynhoven B,Harrigan PR,Götte M
Evidence	This region includes polymerase domain mutations M41L, D67N, K70R, L210W, T215F/Y, and K219Q/E, which are referred to as thymidine analogue-associated mutations (TAMs).

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation