HIV Mutation Detail Information

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Mutation Information
Mutation Site K219N
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Relevant Drug dolutegravir (DTG);lamivudine (LAM)
Literature Information
PubMed PMID 33196554
Published Year 2021
Journal Journal of acquired immune deficiency syndromes (1999)
Title Simulating HIV Breakthrough and Resistance Development During Variable Adherence to Antiretroviral Treatment.
Author Mulato A,Acosta R,Chang S,Martin R,Yant SR,Cihlar T,White K
Evidence MT-2 cells were infected with wild-type or low frequency M184V HIV-1, exposed to drug combinations, monitored for VB, and rebound virus was deep sequenced.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation