|
Mutation Information
|
Mutation Site
|
K219E |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
tenofovir (TDF) |
Literature Information
|
PubMed PMID
|
32295453
|
|
Published Year
|
2020 |
|
Journal
|
Journal of the International Association of Providers of AIDS Care |
|
Title
|
A Review and Clinical Understanding of Tenofovir: Tenofovir Disoproxil Fumarate versus Tenofovir Alafenamide. |
|
Author
|
Wassner C,Bradley N,Lee Y |
|
Evidence
|
The presence of multiple thymidine analog mutations (TAMs), such as M41L, D67N, K70R, L210W, T215Y/F, and K219Q/E, can mediate tenofovir resistance.
|
|
|
HIV Mutation Detail Information