Mutation Information
Mutation Site
|
K219E |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Relevant Drug
|
abacavir (ABC);lamivudine (LAM);dolutegravir (DTG) |
Country
|
French;Italy;Netherlands;Swiss |
Literature Information
PubMed PMID
|
31660328
|
Disease
|
HIV infection/AIDS
|
Published Year
|
2019 |
Journal
|
Open forum infectious diseases |
Title
|
Impact of the M184V/I Mutation on the Efficacy of Abacavir/Lamivudine/Dolutegravir Therapy in HIV Treatment-Experienced Patients. |
Author
|
Olearo F,Nguyen H,Bonnet F,Yerly S,Wandeler G,Stoeckle M,Cavassini M,Scherrer A,Costagiola D,Schmid P,Günthard HF,Bernasconi E,Boeni J,D'arminio Monforte A,Zazzi M,Rossetti B,Neau D,Bellecave P,Rijnders B,Reiss P,Wit F,Kouyos R,Calmy A |
Evidence
|
Information on thymidine analogue mutations (TAMs; M41L, D67N, K70R, L210W, T215Y/F, and K219Q/E) before the switch to ABC/3TC/DTG also was obtained.
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