HIV Mutation Detail Information

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Mutation Information
Mutation Site K219E
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Viral Reference K03455.1
Relevant Drug NRTIs
Literature Information
PubMed PMID 30863788
Disease HIV infection/AIDS
Published Year 2019
Journal Open forum infectious diseases
Title Persistence of Human Immunodeficiency Virus-1 Drug Resistance Mutations in Proviral Deoxyribonucleic Acid After Virologic Failure of Efavirenz-Containing Antiretroviral Regimens.
Author De La Cruz J,Vardhanbhuti S,Sahoo MK,Rovner R,Bosch RJ,Manasa J,Katzenstein DA,Pinsky BA
Evidence We also used deep sequencing to analyze K103N and M184V levels within individuals to assess persistence and decay over time. In most cases, levels remained consistent within the categories of not detected, minority DRM (2%–20%), and >20%.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation