HIV Mutation Detail Information

> K219E Search Result


Mutation Information
Mutation Site K219E
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Relevant Drug efavirenz (EFV);stavudine (D4T);lamivudine (LAM)
Country South Africa
Literature Information
PubMed PMID 21694608
Disease HIV infection/AIDS
Published Year 2011
Journal Journal of acquired immune deficiency syndromes (1999)
Title Genotypic resistance at viral rebound among patients who received lopinavir/ritonavir-based or efavirenz-based first antiretroviral therapy in South Africa.
Author Dlamini JN,Hu Z,Ledwaba J,Morris L,Maldarelli FM,Dewar RL,Highbarger HC,Somaroo H,Sangweni P,Follmann DA,Pau AK,Phidisa II Study Team.
Evidence One participant who received EFV+d4T+3TC had four RT mutations (A62V, K65R, M184V, and K219E) in addition to two NNRTI-associated mutations.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation