Mutation Information
Mutation Site
|
K215N |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
S |
Viral Reference
|
AF282918.1
|
Literature Information
PubMed PMID
|
19812261
|
Published Year
|
2010 |
Journal
|
The Journal of general virology |
Title
|
Biological significance of amino acid substitutions in hepatitis B surface antigen (HBsAg) for glycosylation, secretion, antigenicity and immunogenicity of HBsAg and hepatitis B virus replication. |
Author
|
Wu C,Zhang X,Tian Y,Song J,Yang D,Roggendorf M,Lu M,Chen X |
Evidence
|
The substitutions K122I, T123N and K160N in S-HBsAg in the present study led to the substitutions rtQ476H, rtN477K and rtI515L in HBV polymerase, K285I, T286N and K323N in L-HBsAg, and K178I, T179N and K215N in M-HBsAg,
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