HIV Mutation Detail Information

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Mutation Information
Mutation Site K20T
Mutation Type Amino acid level
Gene/Protein/Region Type PR
Literature Information
PubMed PMID 33093566
Published Year 2020
Journal Scientific reports
Title Nanoscale flow cytometry reveals interpatient variability in HIV protease activity that correlates with viral infectivity and identifies drug-resistant viruses.
Author Bonar MM,Tabler CO,Haqqani AA,Lapointe LE,Galiatsos JA,Joussef-Piña S,Quiñones-Mateu ME,Tilton JC
Evidence 3'Gag + Pol Virus 08-180 had seven major resistance mutations in PR: V32I, M46I, I47V, I54L, V82T, I84V, and L90M and five accessory mutations: K20T, L33F, K43T, G73S, and L89V and was predicted to have high-level resistance to all PIs.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation