|
Mutation Information
|
Mutation Site
|
K19E |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
BMRF1 |
|
Viral Reference
|
V01555.2
|
Literature Information
|
PubMed PMID
|
19801550
|
|
Published Year
|
2009 |
|
Journal
|
The Journal of biological chemistry |
|
Title
|
Crystal structure of epstein-barr virus DNA polymerase processivity factor BMRF1. |
|
Author
|
Murayama K,Nakayama S,Kato-Murayama M,Akasaka R,Ohbayashi N,Kamewari-Hayami Y,Terada T,Shirouzu M,Tsurumi T,Yokoyama S |
|
Evidence
|
To investigate the oligomerization manner and the DNA-binding site, several mutants were prepared as follows: C95E, H141F, C95E/H141F, and C206E for the dimer interface, and K19E, K29E, R87E, K99E, and R257E for the putative DNA binding region.
|
|
|
EBV Mutation Detail Information