Mutation Information
Mutation Site
|
K188R |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
BZLF1 |
Literature Information
PubMed PMID
|
20808903
|
Published Year
|
2010 |
Journal
|
PLoS pathogens |
Title
|
A subset of replication proteins enhances origin recognition and lytic replication by the Epstein-Barr virus ZEBRA protein. |
Author
|
El-Guindy A,Heston L,Miller G |
Evidence
|
These in vitro DNA binding studies clearly indicated that Z(Y180E) and Z(K188A) are both significantly impaired in their capacity to bind to ZEBRA response elements present in regulatory sites for transcription or replication.
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