EBV Mutation Detail Information

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Mutation Information
Mutation Site K188R
Mutation Type Amino acid level
Gene/Protein/Region Type BZLF1
Literature Information
PubMed PMID 20808903
Published Year 2010
Journal PLoS pathogens
Title A subset of replication proteins enhances origin recognition and lytic replication by the Epstein-Barr virus ZEBRA protein.
Author El-Guindy A,Heston L,Miller G
Evidence These in vitro DNA binding studies clearly indicated that Z(Y180E) and Z(K188A) are both significantly impaired in their capacity to bind to ZEBRA response elements present in regulatory sites for transcription or replication.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation