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Mutation Information
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Mutation Site
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K181E |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
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BZLF1 |
Literature Information
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PubMed PMID
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17215287
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Published Year
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2007 |
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Journal
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Journal of virology |
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Title
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Phosphoacceptor site S173 in the regulatory domain of Epstein-Barr Virus ZEBRA protein is required for lytic DNA replication but not for activation of viral early genes. |
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Author
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El-Guindy A,Heston L,Delecluse HJ,Miller G |
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Evidence
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To test whether DNA binding activity was required to maintain the association of the ZEBRA protein with the insoluble fraction, we examined the solubilities of six DNA binding-deficient mutants [Z(K178E), Z(R179E), Z(K181E), Z(N182E), Z(R183E), and Z(S186E)] (18).
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EBV Mutation Detail Information