EBV Mutation Detail Information

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Mutation Information

Mutation Site	K178D
Mutation Type	Amino acid level
Gene/Protein/Region Type	BZLF1

Literature Information

PubMed PMID	21233201
Published Year	2011
Journal	The Journal of biological chemistry
Title	Efficient induction of nuclear aggresomes by specific single missense mutations in the DNA-binding domain of a viral AP-1 homolog.
Author	Park R,Wang'ondu R,Heston L,Shedd D,Miller G
Evidence	Four non-DNA-binding mutants, Z(R179E), Z(R183E), Z(R190E), and Z(K178D) localized to the periphery of large intranuclear spheres, to discrete nuclear aggregates, and to the cytoplasm. Other non-DNA-binding mutants, Z(N182K), Z(N182E), and Z(S186E), did not exhibit this phenotype.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation